Hybrid Fc‐fused interleukin‐7 induces an inflamed tumor microenvironment and improves the efficacy of cancer immunotherapy

OBJECTIVES: Emerging oncotherapeutic strategies require the induction of an immunostimulatory tumor microenvironment (TME) containing numerous tumor‐reactive CD8(+) T cells. Interleukin‐7 (IL‐7), a T‐cell homeostatic cytokine, induces an antitumor response; however, the detailed mechanisms underlyin...

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Detalles Bibliográficos
Autores principales: Kim, Ji‐Hae, Kim, Young‐Min, Choi, Donghoon, Jo, Saet‐byeol, Park, Han Wook, Hong, Sung‐Wook, Park, Sujeong, Kim, Sora, Moon, Sookjin, You, Gihoon, Kang, Yeon‐Woo, Park, Yunji, Lee, Byung Ha, Lee, Seung‐Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507498/
https://www.ncbi.nlm.nih.gov/pubmed/32994996
http://dx.doi.org/10.1002/cti2.1168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507498/
https://www.ncbi.nlm.nih.gov/pubmed/32994996
http://dx.doi.org/10.1002/cti2.1168

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