LRRK2 activation controls the repair of damaged endomembranes in macrophages

Cells respond to endolysosome damage by either repairing the damage or targeting damaged endolysosomes for degradation via lysophagy. However, the signals regulating the decision for repair or lysophagy are poorly characterised. Here, we show that the Parkinson's disease (PD)‐related kinase LRR...

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Detalles Bibliográficos
Autores principales: Herbst, Susanne, Campbell, Philip, Harvey, John, Bernard, Elliott M, Papayannopoulos, Venizelos, Wood, Nicholas W, Morris, Huw R, Gutierrez, Maximiliano G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507578/
https://www.ncbi.nlm.nih.gov/pubmed/32643832
http://dx.doi.org/10.15252/embj.2020104494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507578/
https://www.ncbi.nlm.nih.gov/pubmed/32643832
http://dx.doi.org/10.15252/embj.2020104494

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