A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target

The inhibition of the DNA damage response (DDR) pathway in the treatment of cancer has recently gained interest, and different DDR inhibitors have been developed. Among them, the most promising ones target the WEE1 kinase family, which has a crucial role in cell cycle regulation and DNA damage ident...

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Detalles Bibliográficos
Autores principales: Ghelli Luserna di Rorà, Andrea, Cerchione, Claudio, Martinelli, Giovanni, Simonetti, Giorgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507691/
https://www.ncbi.nlm.nih.gov/pubmed/32958072
http://dx.doi.org/10.1186/s13045-020-00959-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507691/
https://www.ncbi.nlm.nih.gov/pubmed/32958072
http://dx.doi.org/10.1186/s13045-020-00959-2

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