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A proteomic repertoire of autoantigens identified from the classic autoantibody clinical test substrate HEp-2 cells

BACKGROUND: Autoantibodies are a hallmark of autoimmune diseases. Autoantibody screening by indirect immunofluorescence staining of HEp-2 cells with patient sera is a current standard in clinical practice. Differential diagnosis of autoimmune disorders is based on commonly recognizable nuclear and c...

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Detalles Bibliográficos
Autores principales: Wang, Julia Y., Zhang, Wei, Rho, Jung-hyun, Roehrl, Michael W., Roehrl, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507713/
https://www.ncbi.nlm.nih.gov/pubmed/32973414
http://dx.doi.org/10.1186/s12014-020-09298-3