The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models

Particular interest to harness the innate immune system for cancer immunotherapy is fueled by limitations of immune checkpoint blockade. Plasmacytoid dendritic cells (pDC) are detected in a variety of solid tumors and correlate with poor clinical outcome. Release of type I interferons in response to...

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Detalles Bibliográficos
Autores principales: Maser, Ilona-Petra, Hoves, Sabine, Bayer, Christa, Heidkamp, Gordon, Nimmerjahn, Falk, Eckmann, Jan, Ries, Carola H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507800/
https://www.ncbi.nlm.nih.gov/pubmed/33013879
http://dx.doi.org/10.3389/fimmu.2020.02082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507800/
https://www.ncbi.nlm.nih.gov/pubmed/33013879
http://dx.doi.org/10.3389/fimmu.2020.02082

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