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The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models
Particular interest to harness the innate immune system for cancer immunotherapy is fueled by limitations of immune checkpoint blockade. Plasmacytoid dendritic cells (pDC) are detected in a variety of solid tumors and correlate with poor clinical outcome. Release of type I interferons in response to...
Autores principales: | Maser, Ilona-Petra, Hoves, Sabine, Bayer, Christa, Heidkamp, Gordon, Nimmerjahn, Falk, Eckmann, Jan, Ries, Carola H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507800/ https://www.ncbi.nlm.nih.gov/pubmed/33013879 http://dx.doi.org/10.3389/fimmu.2020.02082 |
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