An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19

[Image: see text] SARS-CoV-2 is the viral pathogen causing the COVID19 global pandemic. Consequently, much research has gone into the development of preclinical assays for the discovery of new or repurposing of FDA-approved therapies. Preventing viral entry into a host cell would be an effective ant...

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Detalles Bibliográficos
Autores principales: Shrimp, Jonathan H., Kales, Stephen C., Sanderson, Philip E., Simeonov, Anton, Shen, Min, Hall, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507803/
https://www.ncbi.nlm.nih.gov/pubmed/33062952
http://dx.doi.org/10.1021/acsptsci.0c00106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507803/
https://www.ncbi.nlm.nih.gov/pubmed/33062952
http://dx.doi.org/10.1021/acsptsci.0c00106

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