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An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19
[Image: see text] SARS-CoV-2 is the viral pathogen causing the COVID19 global pandemic. Consequently, much research has gone into the development of preclinical assays for the discovery of new or repurposing of FDA-approved therapies. Preventing viral entry into a host cell would be an effective ant...
Autores principales: | Shrimp, Jonathan H., Kales, Stephen C., Sanderson, Philip E., Simeonov, Anton, Shen, Min, Hall, Matthew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507803/ https://www.ncbi.nlm.nih.gov/pubmed/33062952 http://dx.doi.org/10.1021/acsptsci.0c00106 |
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