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Purification and initial characterization of Plasmodium falciparum K(+) channels, PfKch1 and PfKch2 produced in Saccharomyces cerevisiae

Resistance towards known antimalarial drugs poses a significant problem, urging for novel drugs that target vital proteins in the malaria parasite Plasmodium falciparum. However, recombinant production of malaria proteins is notoriously difficult. To address this, we have investigated two putative K...

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Detalles Bibliográficos
Autores principales: Molbaek, Karen, Tejada, Maria, Ricke, Christina Hoeier, Scharff-Poulsen, Peter, Ellekvist, Peter, Helix-Nielsen, Claus, Kumar, Nirbhay, Klaerke, Dan A., Pedersen, Per Amstrup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507820/
https://www.ncbi.nlm.nih.gov/pubmed/32957994
http://dx.doi.org/10.1186/s12934-020-01437-7