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Purification and initial characterization of Plasmodium falciparum K(+) channels, PfKch1 and PfKch2 produced in Saccharomyces cerevisiae
Resistance towards known antimalarial drugs poses a significant problem, urging for novel drugs that target vital proteins in the malaria parasite Plasmodium falciparum. However, recombinant production of malaria proteins is notoriously difficult. To address this, we have investigated two putative K...
Autores principales: | Molbaek, Karen, Tejada, Maria, Ricke, Christina Hoeier, Scharff-Poulsen, Peter, Ellekvist, Peter, Helix-Nielsen, Claus, Kumar, Nirbhay, Klaerke, Dan A., Pedersen, Per Amstrup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507820/ https://www.ncbi.nlm.nih.gov/pubmed/32957994 http://dx.doi.org/10.1186/s12934-020-01437-7 |
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