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Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma

OBJECTIVES: To explore lymphocyte infiltration as a potential mechanism behind CXCL14-mediated tumor growth suppression in oral cavity squamous cell carcinoma (OSCC). METHODS: We analyzed single cell RNA-sequencing (scRNA-seq) data from OSCC to identify expression changes among malignant cells in ly...

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Detalles Bibliográficos
Autores principales: Parikh, Anuraag, Shin, JuneHo, Faquin, William, Lin, Derrick T, Tirosh, Itay, Sunwoo, John B, Puram, Sidharth V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507891/
https://www.ncbi.nlm.nih.gov/pubmed/32958684
http://dx.doi.org/10.1136/jitc-2020-001048