Genetic Lesions of Type I Interferon Signalling in Human Antiviral Immunity

The concept that type I interferons (IFN-I) are essential to antiviral immunity derives from studies on animal models and cell lines. Virtually all pathogenic viruses have evolved countermeasures to IFN-I restriction, and genetic loss of viral IFN-I antagonists leads to virus attenuation. But just h...

Descripción completa

Detalles Bibliográficos
Autores principales: Duncan, Christopher J.A., Randall, Richard E., Hambleton, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508017/
https://www.ncbi.nlm.nih.gov/pubmed/32977999
http://dx.doi.org/10.1016/j.tig.2020.08.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508017/
https://www.ncbi.nlm.nih.gov/pubmed/32977999
http://dx.doi.org/10.1016/j.tig.2020.08.017

Ejemplares similares