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Ammonium Salt‐Catalyzed Ring‐Opening of Aryl‐Aziridines with β‐Keto Esters

We herein report an ammonium salt‐catalyzed protocol for the regioselective ring opening of aryl‐aziridines with β‐keto esters. The reaction gives access to a variety of highly functionalized target molecules with two consecutive stereogenic centers and can be rendered enantioselective (up to e.r. =...

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Detalles Bibliográficos
Autores principales: Haider, Victoria, Kreuzer, Viktoria, Tiffner, Maximilian, Spingler, Bernhard, Waser, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508174/
https://www.ncbi.nlm.nih.gov/pubmed/32982577
http://dx.doi.org/10.1002/ejoc.202000916