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Excess crossovers impede faithful meiotic chromosome segregation in C. elegans

During meiosis, diploid organisms reduce their chromosome number by half to generate haploid gametes. This process depends on the repair of double strand DNA breaks as crossover recombination events between homologous chromosomes, which hold homologs together to ensure their proper segregation to op...

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Detalles Bibliográficos
Autores principales: Hollis, Jeremy A., Glover, Marissa L., Schlientz, Aleesa J., Cahoon, Cori K., Bowerman, Bruce, Wignall, Sarah M., Libuda, Diana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508374/
https://www.ncbi.nlm.nih.gov/pubmed/32886661
http://dx.doi.org/10.1371/journal.pgen.1009001