Glycogen phosphorylase inhibitor, 2,3‐bis[(2E)‐3‐(4‐hydroxyphenyl)prop‐2‐enamido] butanedioic acid (BF142), improves baseline insulin secretion of MIN6 insulinoma cells

Type 2 diabetes mellitus (T2DM), one of the most common metabolic diseases, is characterized by insulin resistance and inadequate insulin secretion of β cells. Glycogen phosphorylase (GP) is the key enzyme in glycogen breakdown, and contributes to hepatic glucose production during fasting or during...

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Detalles Bibliográficos
Autores principales: Nagy, Lilla, Béke, Ferenc, Juhász, László, Kovács, Tünde, Juhász-Tóth, Éva, Docsa, Tibor, Tóth, Attila, Gergely, Pál, Somsák, László, Bai, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508380/
https://www.ncbi.nlm.nih.gov/pubmed/32960890
http://dx.doi.org/10.1371/journal.pone.0236081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508380/
https://www.ncbi.nlm.nih.gov/pubmed/32960890
http://dx.doi.org/10.1371/journal.pone.0236081

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