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Doxorubicin-induced p53 interferes with mitophagy in cardiac fibroblasts

Anthracyclines are the critical component in a majority of pediatric chemotherapy regimens due to their broad anticancer efficacy. Unfortunately, the vast majority of long-term childhood cancer survivors will develop a chronic health condition caused by their successful treatments and severe cardiac...

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Detalles Bibliográficos
Autores principales: Mancilla, T. R., Davis, L. R., Aune, G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508395/
https://www.ncbi.nlm.nih.gov/pubmed/32960902
http://dx.doi.org/10.1371/journal.pone.0238856