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Doxorubicin-induced p53 interferes with mitophagy in cardiac fibroblasts
Anthracyclines are the critical component in a majority of pediatric chemotherapy regimens due to their broad anticancer efficacy. Unfortunately, the vast majority of long-term childhood cancer survivors will develop a chronic health condition caused by their successful treatments and severe cardiac...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508395/ https://www.ncbi.nlm.nih.gov/pubmed/32960902 http://dx.doi.org/10.1371/journal.pone.0238856 |