RAD51 Inhibitor Reverses Etoposide-Induced Genomic Toxicity and Instability in Esophageal Adenocarcinoma Cells

AIM: In normal cells, homologous recombination (HR) is strictly regulated and precise and plays an important role in preserving genomic integrity by accurately repairing DNA damage. RAD51 is the recombinase which mediates homologous base pairing and strand exchange during DNA repair by HR. We have p...

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Detalles Bibliográficos
Autores principales: Liao, Chengcheng, Zhao, Jiangning, Kumar, Subodh, Chakraborty, Chandraditya, Talluri, Srikanth, Munshi, Nikhil C., Shammas, Masood A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508453/
https://www.ncbi.nlm.nih.gov/pubmed/32968740
http://dx.doi.org/10.46439/toxicology.2.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508453/
https://www.ncbi.nlm.nih.gov/pubmed/32968740
http://dx.doi.org/10.46439/toxicology.2.006

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