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CRISPR-Cas systems: Overview, innovations and applications in human disease research and gene therapy

Genome editing is the modification of genomic DNA at a specific target site in a wide variety of cell types and organisms, including insertion, deletion and replacement of DNA, resulting in inactivation of target genes, acquisition of novel genetic traits and correction of pathogenic gene mutations....

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Detalles Bibliográficos
Autores principales: Xu, Yuanyuan, Li, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508700/
https://www.ncbi.nlm.nih.gov/pubmed/33005303
http://dx.doi.org/10.1016/j.csbj.2020.08.031