A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation

Polycomb and Trithorax group proteins maintain stable epigenetic memory of gene expression states for some genes, but many targets show highly dynamic regulation. Here we combine experiment and theory to examine the mechanistic basis of these different modes of regulation. We present a mathematical...

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Detalles Bibliográficos
Autores principales: Reinig, Jeannette, Ruge, Frank, Howard, Martin, Ringrose, Leonie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508846/
https://www.ncbi.nlm.nih.gov/pubmed/32963223
http://dx.doi.org/10.1038/s41467-020-18507-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508846/
https://www.ncbi.nlm.nih.gov/pubmed/32963223
http://dx.doi.org/10.1038/s41467-020-18507-4

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