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Effects of optogenetic stimulation of basal forebrain parvalbumin neurons on Alzheimer’s disease pathology

Neuronal activity can modify Alzheimer’s disease pathology. Overexcitation of neurons can facilitate disease progression whereas the induction of cortical gamma oscillations can reduce amyloid load and improve cognitive functions in mouse models. Although previous studies have induced cortical gamma...

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Detalles Bibliográficos
Autores principales: Wilson, Caroline A., Fouda, Sarah, Sakata, Shuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508947/
https://www.ncbi.nlm.nih.gov/pubmed/32963298
http://dx.doi.org/10.1038/s41598-020-72421-9