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Effects of optogenetic stimulation of basal forebrain parvalbumin neurons on Alzheimer’s disease pathology
Neuronal activity can modify Alzheimer’s disease pathology. Overexcitation of neurons can facilitate disease progression whereas the induction of cortical gamma oscillations can reduce amyloid load and improve cognitive functions in mouse models. Although previous studies have induced cortical gamma...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508947/ https://www.ncbi.nlm.nih.gov/pubmed/32963298 http://dx.doi.org/10.1038/s41598-020-72421-9 |