Pancreatic β-cells respond to fuel pressure with an early metabolic switch

Pancreatic β-cells become irreversibly damaged by long-term exposure to excessive glucose concentrations and lose their ability to carry out glucose stimulated insulin secretion (GSIS) upon damage. The β-cells are not able to control glucose uptake and they are therefore left vulnerable for endogeno...

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Detalles Bibliográficos
Autores principales: Malinowski, Ronja M., Ghiasi, Seyed M., Mandrup-Poulsen, Thomas, Meier, Sebastian, Lerche, Mathilde H., Ardenkjær-Larsen, Jan H., Jensen, Pernille R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508987/
https://www.ncbi.nlm.nih.gov/pubmed/32963286
http://dx.doi.org/10.1038/s41598-020-72348-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508987/
https://www.ncbi.nlm.nih.gov/pubmed/32963286
http://dx.doi.org/10.1038/s41598-020-72348-1

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