Spinal cord atrophy in a primary progressive multiple sclerosis trial: Improved sample size using GBSI

BACKGROUND: We aimed to evaluate the implications for clinical trial design of the generalised boundary-shift integral (GBSI) for spinal cord atrophy measurement. METHODS: We included 220 primary-progressive multiple sclerosis patients from a phase 2 clinical trial, with baseline and week-48 3DT1-we...

Descripción completa

Detalles Bibliográficos
Autores principales: Moccia, Marcello, Valsecchi, Nicola, Ciccarelli, Olga, Van Schijndel, Ronald, Barkhof, Frederik, Prados, Ferran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509079/
https://www.ncbi.nlm.nih.gov/pubmed/32961403
http://dx.doi.org/10.1016/j.nicl.2020.102418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509079/
https://www.ncbi.nlm.nih.gov/pubmed/32961403
http://dx.doi.org/10.1016/j.nicl.2020.102418

Ejemplares similares