Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells

The use of human mesenchymal stem cells (hMSCs) in clinical applications requires large-scale cell expansion prior to administration. However, the prolonged culture of hMSCs results in cellular senescence, impairing their proliferation and therapeutic potentials. To understand the role of microRNAs...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Yi-deun, Park, Seul-Ki, Kang, Dayeon, Hwang, Supyong, Kang, Myoung-Hee, Hong, Seung-Woo, Moon, Jai-Hee, Shin, Jae-Sik, Jin, Dong-Hoon, You, Dalsan, Lee, Joo-Yong, Park, Yun-Yong, Hwang, Jung Jin, Kim, Choung Soo, Suh, Nayoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509080/
https://www.ncbi.nlm.nih.gov/pubmed/32961441
http://dx.doi.org/10.1016/j.redox.2020.101716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509080/
https://www.ncbi.nlm.nih.gov/pubmed/32961441
http://dx.doi.org/10.1016/j.redox.2020.101716

Ejemplares similares