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VEGFR2 Promotes Metastasis and PD-L2 Expression of Human Osteosarcoma Cells by Activating the STAT3 and RhoA-ROCK-LIMK2 Pathways

The survival rate of osteosarcoma, the most prevalent primary bone tumor, has not been effectively improved in the last 30 years. Hence, new treatments and drugs are urgently needed. Antiangiogenic therapy and immunotherapy have good antitumor effects in many kinds of tumors. It is hypothesized that...

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Detalles Bibliográficos
Autores principales: Zheng, Bingxin, Zhou, Chuanli, Qu, Guojian, Ren, Chongmin, Yan, Peng, Guo, Wei, Yue, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509134/
https://www.ncbi.nlm.nih.gov/pubmed/33014879
http://dx.doi.org/10.3389/fonc.2020.543562