RskA Is a Dual Function Activator-Inhibitor That Controls SigK Activity Across Distinct Bacterial Genera

It has been previously shown that RskA, the anti-Sigma factor K of Mycobacterium tuberculosis, inhibits SigK and that mutations in RskA promote high expression of the SigK regulon. The latter observation led us to hypothesize that RskA mutations lead to loss of the anti-Sigma factor function. In thi...

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Detalles Bibliográficos
Autores principales: Veyrier, Frédéric J., Nieves, Cecilia, Lefrancois, Louise H., Trigui, Hana, Vincent, Antony T., Behr, Marcel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509140/
https://www.ncbi.nlm.nih.gov/pubmed/33013790
http://dx.doi.org/10.3389/fmicb.2020.558166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509140/
https://www.ncbi.nlm.nih.gov/pubmed/33013790
http://dx.doi.org/10.3389/fmicb.2020.558166

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