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Pathway-Based Drug Response Prediction Using Similarity Identification in Gene Expression

Lapatinib and trastuzumab (Herceptin) are targeted therapies designed for patients with HER2+ breast tumors. Although these therapies improved survival rates of patients with this tumor type, not all the patients harboring HER2 amplification respond to these drugs. The NeoALTTO clinical trial was de...

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Detalles Bibliográficos
Autores principales: Madani Tonekaboni, Seyed Ali, Beri, Gangesh, Haibe-Kains, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509171/
https://www.ncbi.nlm.nih.gov/pubmed/33033492
http://dx.doi.org/10.3389/fgene.2020.01016