Chan–Evans–Lam N1-(het)arylation and N1-alkеnylation of 4-fluoroalkylpyrimidin-2(1H)-ones

The Chan–Evans–Lam reaction of 1-unsubstituted 4-fluoroalkylpyrimidin-2(1Н)-ones with arylboronic acids is reported as a facile synthetic route to hitherto unavailable N1-(het)aryl and N1-alkenyl derivatives of the corresponding pyrimidines. An efficient C–N bond-forming process is also observed by...

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Detalles Bibliográficos
Autores principales: Tkachuk, Viktor M, Lukianov, Oleh O, Vovk, Mykhailo V, Gillaizeau, Isabelle, Sukach, Volodymyr A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509380/
https://www.ncbi.nlm.nih.gov/pubmed/33014170
http://dx.doi.org/10.3762/bjoc.16.191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509380/
https://www.ncbi.nlm.nih.gov/pubmed/33014170
http://dx.doi.org/10.3762/bjoc.16.191

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