Construction of a Live-Attenuated Vaccine Strain of Yersinia pestis EV76-B-SHUΔpla and Evaluation of Its Protection Efficacy in a Mouse Model by Aerosolized Intratracheal Inoculation

Plague, which is caused by Yersinia pestis, is one of the most dangerous infectious diseases. No FDA-approved vaccine against plague is available for human use at present. To improve the immune safety of Y. pestis EV76 based live attenuated vaccine and to explore the feasibility of aerosolized intra...

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Detalles Bibliográficos
Autores principales: Feng, Junxia, Deng, Yingying, Fu, Mengjiao, Hu, Xueyuan, Luo, Wenbo, Lu, Zhiyu, Dai, Lupeng, Yang, Huiying, Zhao, Xiaodong, Du, Zongmin, Wen, Bohai, Jiang, Lingxiao, Zhou, Dongsheng, Jiao, Jun, Xiong, Xiaolu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509399/
https://www.ncbi.nlm.nih.gov/pubmed/33014895
http://dx.doi.org/10.3389/fcimb.2020.00473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509399/
https://www.ncbi.nlm.nih.gov/pubmed/33014895
http://dx.doi.org/10.3389/fcimb.2020.00473

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