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The Discovery and Characterization of Targeted Perikaryal-Specific Brain Lesions With Excitotoxins

The neurotoxic action of glutamic acid was first described by Lucas and Newhouse, who demonstrated neural degeneration in the inner layers of the neonatal mouse retina after systemic treatment with L-glutamate. Olney extended these findings by showing that neuronal degeneration affected other brain...

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Detalles Bibliográficos
Autores principales: Coyle, Joseph T., Schwarcz, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509407/
https://www.ncbi.nlm.nih.gov/pubmed/33013307
http://dx.doi.org/10.3389/fnins.2020.00927