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An MRTF-A–Sp1–PDE5 Axis Mediates Angiotensin-II-Induced Cardiomyocyte Hypertrophy

Cardiac hypertrophy is a critical intermediate step in the pathogenesis of heart failure. A myriad of signaling networks converge on cardiomyocytes to elicit hypertrophic growth in response to various injurious stimuli. In the present study, we investigated the cardiomyocyte-specific role of myocard...

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Detalles Bibliográficos
Autores principales: Wu, Teng, Wang, Huidi, Xin, Xiaojun, Zhang, Tianyi, Hou, Yannan, Fang, Mingming, Lu, Xiang, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509415/
https://www.ncbi.nlm.nih.gov/pubmed/33015041
http://dx.doi.org/10.3389/fcell.2020.00839