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Pro-inflammatory Stimulation of Monocytes by ANCA Is Linked to Changes in Cellular Metabolism

Clinical and experimental data suggest that pathogenesis in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is driven by ANCA-mediated activation of neutrophils and monocytes. While the role of neutrophils has been extensively investigated, the function of monocytes remains relativ...

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Detalles Bibliográficos
Autores principales: O'Brien, Eóin C., White, Carla A., Wyse, Jason, Leacy, Emma, Porter, Richard K., Little, Mark A., Hickey, Fionnuala B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509421/
https://www.ncbi.nlm.nih.gov/pubmed/33015103
http://dx.doi.org/10.3389/fmed.2020.00553