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Concomitant Mutations in EGFR 19Del/L858R Mutation and Their Association with Response to EGFR-TKIs in NSCLC Patients

OBJECTIVE: Differences in efficacy of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI) have been observed between non-small cell lung cancer (NSCLC) patients with 19 exon deletion (19Del) and L858R mutation. We explored whether the total number or pattern of concomitant mutatio...

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Detalles Bibliográficos
Autores principales: Liang, Hengrui, Li, Caichen, Zhao, Yi, Zhao, Shen, Huang, Jun, Cai, Xiuyu, Cheng, Bo, Xiong, Shan, Li, Jianfu, Wang, Wei, Zhu, Changbin, Li, Weiwei, He, Jianxing, Liang, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509478/
https://www.ncbi.nlm.nih.gov/pubmed/32982456
http://dx.doi.org/10.2147/CMAR.S255967