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Microflow-Based Device for In Vitro and Ex Vivo Drug Permeability Studies

This paper presents a novel microflow-based concept for studying the permeability of in vitro cell models or ex vivo tissues. Using the proposed concept, we demonstrate how to maintain physiologically relevant test conditions and produce highly reproducible permeability values for a range (31) of dr...

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Detalles Bibliográficos
Autores principales: Hemmilä, Samu, Ruponen, Marika, Toropainen, Elisa, Tengvall-Unadike, Unni, Urtti, Arto, Kallio, Pasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509603/
https://www.ncbi.nlm.nih.gov/pubmed/32351160
http://dx.doi.org/10.1177/2472630320916190