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Stiffness of HIV‐1 Mimicking Polymer Nanoparticles Modulates Ganglioside‐Mediated Cellular Uptake and Trafficking

The monosialodihexosylganglioside, GM3, and its binding to CD169 (Siglec‐1) have been indicated as key factors in the glycoprotein‐independent sequestration of the human immunodeficiency virus‐1 (HIV‐1) in virus‐containing compartments (VCCs) in myeloid cells. Here, lipid‐wrapped polymer nanoparticl...

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Detalles Bibliográficos
Autores principales: Eshaghi, Behnaz, Alsharif, Nourin, An, Xingda, Akiyama, Hisashi, Brown, Keith A., Gummuluru, Suryaram, Reinhard, Björn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509657/
https://www.ncbi.nlm.nih.gov/pubmed/32999830
http://dx.doi.org/10.1002/advs.202000649