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Stiffness of HIV‐1 Mimicking Polymer Nanoparticles Modulates Ganglioside‐Mediated Cellular Uptake and Trafficking
The monosialodihexosylganglioside, GM3, and its binding to CD169 (Siglec‐1) have been indicated as key factors in the glycoprotein‐independent sequestration of the human immunodeficiency virus‐1 (HIV‐1) in virus‐containing compartments (VCCs) in myeloid cells. Here, lipid‐wrapped polymer nanoparticl...
Autores principales: | Eshaghi, Behnaz, Alsharif, Nourin, An, Xingda, Akiyama, Hisashi, Brown, Keith A., Gummuluru, Suryaram, Reinhard, Björn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509657/ https://www.ncbi.nlm.nih.gov/pubmed/32999830 http://dx.doi.org/10.1002/advs.202000649 |
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