Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE Dysfunction

PURPOSE: To study if human embryonic stem cell–derived photoreceptors could survive and function without the support of retinal pigment epithelium (RPE) after transplantation into Royal College of Surgeons rats, a rat model of retinal degeneration caused by RPE dysfunction. METHODS: CSC14 human embr...

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Detalles Bibliográficos
Autores principales: Lin, Bin, McLelland, Bryce T., Aramant, Robert B., Thomas, Biju B., Nistor, Gabriel, Keirstead, Hans S., Seiler, Magdalene J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509771/
https://www.ncbi.nlm.nih.gov/pubmed/32945842
http://dx.doi.org/10.1167/iovs.61.11.34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509771/
https://www.ncbi.nlm.nih.gov/pubmed/32945842
http://dx.doi.org/10.1167/iovs.61.11.34

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