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Interaction between adverse childhood experiences and polygenic risk in patients with bipolar disorder

The interaction between genes and environment often occurs when they depend on one another. We hypothesized that adverse childhood experiences (ACEs) would interact with genetic predispositions to bipolar disorder (BD), demonstrating earlier age at onset (AAO) and worse clinical outcomes. We aimed t...

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Detalles Bibliográficos
Autores principales: Park, Young-Min, Shekhtman, Tatyana, Kelsoe, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509781/
https://www.ncbi.nlm.nih.gov/pubmed/32963226
http://dx.doi.org/10.1038/s41398-020-01010-1