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Interaction between adverse childhood experiences and polygenic risk in patients with bipolar disorder
The interaction between genes and environment often occurs when they depend on one another. We hypothesized that adverse childhood experiences (ACEs) would interact with genetic predispositions to bipolar disorder (BD), demonstrating earlier age at onset (AAO) and worse clinical outcomes. We aimed t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509781/ https://www.ncbi.nlm.nih.gov/pubmed/32963226 http://dx.doi.org/10.1038/s41398-020-01010-1 |