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Derivation and propagation of spermatogonial stem cells from human pluripotent cells

OBJECTIVES: This study is designed to generate and propagate human spermatogonial stem cells (SSCs) derived from human pluripotent stem cells (hPSCs). METHODS: hPSCs were differentiated into SSC-like cells (SSCLCs) by a three-step strategy. The biological characteristics of SSCLCs were detected by i...

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Detalles Bibliográficos
Autores principales: Xu, Huiming, Yang, Mengbo, Tian, Ruhui, Wang, Yonghui, Liu, Linhong, Zhu, Zijue, Yang, Shi, Yuan, Qingqing, Niu, Minghui, Yao, Chencheng, Zhi, Erlei, Li, Peng, Zhou, Chenhao, He, Zuping, Li, Zheng, Gao, Wei-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509941/
https://www.ncbi.nlm.nih.gov/pubmed/32967715
http://dx.doi.org/10.1186/s13287-020-01896-0