Methylation changes at the GNAS imprinted locus in pancreatic cystic neoplasms are important for the diagnosis of malignant cysts

BACKGROUND: Guanine nucleotide-binding protein, alpha stimulating (GNAS) mutations are characteristic of intraductal papillary mucinous neoplasms (IPMNs). Pancreatic ductal adenocarcinomas (PDACs) harboring GNAS mutations originate in IPMNs. GNAS is a complex imprinted locus that produces five trans...

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Detalles Bibliográficos
Autores principales: Faias, Sandra, Duarte, Marlene, Pereira, Luísa, Chaves, Paula, Cravo, Marília, Dias Pereira, Antonio, Albuquerque, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Observational Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510000/
https://www.ncbi.nlm.nih.gov/pubmed/33005298
http://dx.doi.org/10.4251/wjgo.v12.i9.1056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510000/
https://www.ncbi.nlm.nih.gov/pubmed/33005298
http://dx.doi.org/10.4251/wjgo.v12.i9.1056

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