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A deconvolution method and its application in analyzing the cellular fractions in acute myeloid leukemia samples

BACKGROUND: The identification of cell type-specific genes (markers) is an essential step for the deconvolution of the cellular fractions, primarily, from the gene expression data of a bulk sample. However, the genes with significant changes identified by pair-wise comparisons cannot indeed represen...

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Detalles Bibliográficos
Autores principales: Li, Huamei, Sharma, Amit, Ming, Wenglong, Sun, Xiao, Liu, Hongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510109/
https://www.ncbi.nlm.nih.gov/pubmed/32967610
http://dx.doi.org/10.1186/s12864-020-06888-1