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A deconvolution method and its application in analyzing the cellular fractions in acute myeloid leukemia samples
BACKGROUND: The identification of cell type-specific genes (markers) is an essential step for the deconvolution of the cellular fractions, primarily, from the gene expression data of a bulk sample. However, the genes with significant changes identified by pair-wise comparisons cannot indeed represen...
Autores principales: | Li, Huamei, Sharma, Amit, Ming, Wenglong, Sun, Xiao, Liu, Hongde |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510109/ https://www.ncbi.nlm.nih.gov/pubmed/32967610 http://dx.doi.org/10.1186/s12864-020-06888-1 |
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