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Site-specific opening of the blood-brain barrier by extracellular histones

BACKGROUND: Increased extracellular histones in the bloodstream are known as a biomarker for vascular dysfunction associated with severe trauma or sepsis. There is limited information regarding the pathogenic role of circulating histones in neuroinflammation and cerebrovascular endothelial injury. P...

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Detalles Bibliográficos
Autores principales: Villalba, Nuria, Baby, Sheon, Cha, Byeong J., Yuan, Sarah Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510151/
https://www.ncbi.nlm.nih.gov/pubmed/32962721
http://dx.doi.org/10.1186/s12974-020-01950-x