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AHRR methylation in heavy smokers: associations with smoking, lung cancer risk, and lung cancer mortality

BACKGROUND: A low level of methylation at cg05575921 in the aryl-hydrocarbon receptor repressor (AHRR) gene is robustly associated with smoking, and some studies have observed associations between cg05575921 methylation and increased lung cancer risk and mortality. To prospectively examine whether d...

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Detalles Bibliográficos
Autores principales: Grieshober, Laurie, Graw, Stefan, Barnett, Matt J., Thornquist, Mark D., Goodman, Gary E., Chen, Chu, Koestler, Devin C., Marsit, Carmen J., Doherty, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510160/
https://www.ncbi.nlm.nih.gov/pubmed/32962699
http://dx.doi.org/10.1186/s12885-020-07407-x