MET and RON receptor tyrosine kinases in colorectal adenocarcinoma: molecular features as drug targets and antibody-drug conjugates for therapy

Advanced colorectal adenocarcinoma (CRAC), featured by distinctive histopathological appearance, distant organ metastasis, acquired chemoresistance, and tumorigenic stemness is a group of heterogeneous cancers with unique genetic signatures and malignant phenotypes. Treatment of CRAC is a daunting t...

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Detalles Bibliográficos
Autores principales: Yao, Hang-Ping, Tong, Xiang-Min, Hudson, Rachel, Wang, Ming-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510328/
https://www.ncbi.nlm.nih.gov/pubmed/32962738
http://dx.doi.org/10.1186/s13046-020-01711-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510328/
https://www.ncbi.nlm.nih.gov/pubmed/32962738
http://dx.doi.org/10.1186/s13046-020-01711-x

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