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Inhibition of myeloperoxidase increases revascularization and improves blood flow in a diabetic mouse model of hindlimb ischaemia

OBJECTIVE: Diabetes mellitus is a significant risk factor for peripheral artery disease. Diabetes mellitus induces chronic states of oxidative stress and vascular inflammation that increase neutrophil activation and release of myeloperoxidase. The goal of this study is to determine whether inhibitin...

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Detalles Bibliográficos
Autores principales: Weihrauch, Dorothee, Martin, Dustin P, Jones, Deron, Krolikowski, John, Struve, Janine, Naylor, Stephen, Pritchard, Kirkwood A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510377/
https://www.ncbi.nlm.nih.gov/pubmed/32223319
http://dx.doi.org/10.1177/1479164120907971