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Inhibition of myeloperoxidase increases revascularization and improves blood flow in a diabetic mouse model of hindlimb ischaemia
OBJECTIVE: Diabetes mellitus is a significant risk factor for peripheral artery disease. Diabetes mellitus induces chronic states of oxidative stress and vascular inflammation that increase neutrophil activation and release of myeloperoxidase. The goal of this study is to determine whether inhibitin...
Autores principales: | Weihrauch, Dorothee, Martin, Dustin P, Jones, Deron, Krolikowski, John, Struve, Janine, Naylor, Stephen, Pritchard, Kirkwood A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510377/ https://www.ncbi.nlm.nih.gov/pubmed/32223319 http://dx.doi.org/10.1177/1479164120907971 |
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