Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis

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BACKGROUND: Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Here, we determined how aging contributes to the altered gene expression related to mitochondrial function, cellular senescence, and telomeric leng...

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Detalles Bibliográficos
Autores principales: Maremanda, Krishna P., Sundar, Isaac K., Li, Dongmei, Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510459/
https://www.ncbi.nlm.nih.gov/pubmed/33013423
http://dx.doi.org/10.3389/fphar.2020.584637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510459/
https://www.ncbi.nlm.nih.gov/pubmed/33013423
http://dx.doi.org/10.3389/fphar.2020.584637

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