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The effect of size, charge, and peptide ligand length on kidney targeting by small, organic nanoparticles

Chronic kidney disease (CKD) affects 15% of the US adult population. However, most clinically available drugs for CKD show low bioavailability to the kidneys and non‐specific uptake by other organs which results in adverse side effects. Hence, a targeted, drug delivery strategy to enhance kidney dru...

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Detalles Bibliográficos
Autores principales: Huang, Yi, Jiang, Kairui, Zhang, Xuting, Chung, Eun Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510478/
https://www.ncbi.nlm.nih.gov/pubmed/33005739
http://dx.doi.org/10.1002/btm2.10173