Cargando…
The effect of size, charge, and peptide ligand length on kidney targeting by small, organic nanoparticles
Chronic kidney disease (CKD) affects 15% of the US adult population. However, most clinically available drugs for CKD show low bioavailability to the kidneys and non‐specific uptake by other organs which results in adverse side effects. Hence, a targeted, drug delivery strategy to enhance kidney dru...
Autores principales: | Huang, Yi, Jiang, Kairui, Zhang, Xuting, Chung, Eun Ji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510478/ https://www.ncbi.nlm.nih.gov/pubmed/33005739 http://dx.doi.org/10.1002/btm2.10173 |
Ejemplares similares
-
Evaluation of kidney size in children: a pilot study of renal length as a surrogate of organ growth
por: Kim, Boo Won, et al.
Publicado: (2012) -
Substituent, Charge, and Size Effects on the Fluorogenic
Performance of Amyloid Ligands: A Small-Library Screening Study
por: Donabedian, Patrick L., et al.
Publicado: (2017) -
The role of nanoparticle size and ligand coverage in size focusing of colloidal metal nanoparticles
por: Mozaffari, Saeed, et al.
Publicado: (2019) -
Immunotoxicity of silicon dioxide nanoparticles with different sizes and electrostatic charge
por: Kim, Jae-Hyun, et al.
Publicado: (2014) -
Introduction of lactobionic acid ligand into mixed-charge nanoparticles to realize in situ triggered active targeting to hepatoma cells
por: Li, H., et al.
Publicado: (2019)