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Pharmacodynamic effects of the K(+) binder patiromer in a novel chronic hyperkalemia model in spontaneously hypertensive rats

Currently described hyperkalemia (HK) animal models are typically acute and cause significant distress and mortality to the animals, warranting new approaches for studying chronic HK in a more appropriate clinical setting. Using the spontaneously hypertensive rat (SHR) model as a more relevant disea...

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Detalles Bibliográficos
Autores principales: Iyer, Sai Prasad N., Lee, Lawrence, Li, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510565/
https://www.ncbi.nlm.nih.gov/pubmed/32965782
http://dx.doi.org/10.14814/phy2.14572